Antimicrobial coating innovations to prevent healthcare-associated infection

Healthcare associated infection: novel strategies and antimicrobial implants to prevent surgical site infection.

This report is based on a Hygienist Panel Meeting held at St Anne's Manor, Wokingham on 24-25 June 2009. The panel agreed that greater use should be made of antiseptics to reduce reliance on antibiotics with their associated risk of antibiotic resistance. When choosing an antiseptic for clinical use, the Biocompatibility Index, which considers both the microbiocidal activity and any cytotoxic e...

In vivo efficacy of a silicone‒cationic steroid antimicrobial coating to prevent implant-related infection.

Active release antimicrobial coatings for medical devices have been developed to prevent and treat biofilm implant-related infections. To date, only a handful of coatings have been put into clinical use, with limited success. In this study, a novel antimicrobial compound was incorporated into a silicone (polydimethylsiloxane or PDMS) polymer to develop a novel active release coating that addres...

Using PHMB antimicrobial to prevent wound infection

It has been estimated that 15% of patients who have elective surgery and 30% of patients whose surgery was classed as ‘contaminated’ suffer from surgical site infections (SSIs) (Bruce et al, 2001). Patients with SSIs will have extended hospital stays, they will have a greater risk of morbidity and mortality, and treatment costs will be increased (Kirkland et al, 1999). Wound management programm...

Can antimicrobial central venous catheters prevent associated infection?

a survey of adherence to guidelines to prevent healthcare-associated infections in iranian intensive care units

conclusions evidence-based post-insertion recommended care practices were not consistently and uniformly implemented in the intensive care units. establishment of a program for the surveillance of adherence to recommended guidelines is required for improving compliance by health professionals and the quality of preventive care. background healthcare-associated infections (hais) are acquired by ...